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1.
Progression-free survival and safety at 3.5 years of follow-up: results from the randomized phase 3 PRIMA/ENGOT-OV26/GOG-3012 trial of niraparib maintenance treatment in patients with newly diagnosed ovarian cancer - a plain language summary.
Future Oncol
; 2024 Mar 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-38501262
2.
Prospective evaluation of the tolerability and efficacy of niraparib dosing based on baseline body weight and platelet count: Results from the PRIMA/ENGOT-OV26/GOG-3012 trial.
Cancer
; 129(12): 1846-1855, 2023 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-37060236
3.
Optimizing disease progression assessment using blinded central independent review and comparing it with investigator assessment in the PRIMA/ENGOT-ov26/GOG-3012 trial: challenges and solutions.
Int J Gynecol Cancer
; 33(11): 1733-1742, 2023 11 06.
Artículo
en Inglés
| MEDLINE | ID: mdl-37931976
4.
Niraparib in Patients with Newly Diagnosed Advanced Ovarian Cancer.
N Engl J Med
; 381(25): 2391-2402, 2019 12 19.
Artículo
en Inglés
| MEDLINE | ID: mdl-31562799
5.
Efficacy of niraparib by time of surgery and postoperative residual disease status: A post hoc analysis of patients in the PRIMA/ENGOT-OV26/GOG-3012 study.
Gynecol Oncol
; 166(1): 36-43, 2022 07.
Artículo
en Inglés
| MEDLINE | ID: mdl-35550709
6.
Systematic literature review of efficacy and safety of first-line maintenance therapy trials in advanced ovarian cancer.
Future Oncol
; 18(30): 3435-3447, 2022 Sep.
Artículo
en Inglés
| MEDLINE | ID: mdl-36102225
7.
Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development.
PLoS Genet
; 12(8): e1006242, 2016 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-27494029
8.
A shower of second hit events as the cause of multifocal renal cell carcinoma in tuberous sclerosis complex.
Hum Mol Genet
; 24(7): 1836-42, 2015 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-25432535
9.
Rapamycin-resistant poly (ADP-ribose) polymerase-1 overexpression is a potential therapeutic target in lymphangioleiomyomatosis.
Am J Respir Cell Mol Biol
; 51(6): 738-49, 2014 Dec.
Artículo
en Inglés
| MEDLINE | ID: mdl-24874429
10.
Graded loss of tuberin in an allelic series of brain models of TSC correlates with survival, and biochemical, histological and behavioral features.
Hum Mol Genet
; 21(19): 4286-300, 2012 Oct 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22752306
11.
Regulable neural progenitor-specific Tsc1 loss yields giant cells with organellar dysfunction in a model of tuberous sclerosis complex.
Proc Natl Acad Sci U S A
; 108(45): E1070-9, 2011 Nov 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-22025691
12.
A Relative Bioavailability, Bioequivalence, and Food Effect Study of Niraparib Tablets in Patients with Advanced Solid Tumors.
Clin Ther
; 46(3): 228-238, 2024 03.
Artículo
en Inglés
| MEDLINE | ID: mdl-38423866
13.
Extrarenal perivascular epithelioid cell tumors (PEComas) respond to mTOR inhibition: clinical and molecular correlates.
Int J Cancer
; 132(7): 1711-7, 2013 Apr 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-22927055
14.
Progression-free survival and safety at 3.5years of follow-up: results from the randomised phase 3 PRIMA/ENGOT-OV26/GOG-3012 trial of niraparib maintenance treatment in patients with newly diagnosed ovarian cancer.
Eur J Cancer
; 189: 112908, 2023 08.
Artículo
en Inglés
| MEDLINE | ID: mdl-37263896
15.
Evaluation of Hsp90 and mTOR inhibitors as potential drugs for the treatment of TSC1/TSC2 deficient cancer.
PLoS One
; 16(4): e0248380, 2021.
Artículo
en Inglés
| MEDLINE | ID: mdl-33891611
16.
Leydig cell tumor of the testis in tuberous sclerosis: lack of second hit events.
Oncologist
; 17(7): 927-9, 2012.
Artículo
en Inglés
| MEDLINE | ID: mdl-22707517
17.
p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.
Cancer Res
; 77(12): 3255-3267, 2017 06 15.
Artículo
en Inglés
| MEDLINE | ID: mdl-28512249
18.
Correction: p62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis.
Cancer Res
; 80(23): 5424, 2020 Dec 01.
Artículo
en Inglés
| MEDLINE | ID: mdl-33268556
19.
Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide.
Mol Cancer Res
; 12(1): 48-57, 2014 Jan.
Artículo
en Inglés
| MEDLINE | ID: mdl-24296756
20.
Similar trends in serum VEGF-D levels and kidney angiomyolipoma responses with longer duration sirolimus treatment in adults with tuberous sclerosis.
PLoS One
; 8(2): e56199, 2013.
Artículo
en Inglés
| MEDLINE | ID: mdl-23437092
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